Foods with Function Claims: Empirical studies for "Mibyo (presymptomatic state) prevention", "Health Promotion", "Become healthy", "Can walk lightly" and "Rejuvenate" by intake of eggshell membrane dietary supplement, TO-II BEAUTY EVOLUTION

Foods with Function Claims: Empirical studies for "Mibyo (presymptomatic state) prevention", "Health Promotion", "Become healthy", "Can walk lightly" and "Rejuvenate" by intake of eggshell membrane dietary supplement, TO-II BEAUTY EVOLUTION - Empirical studies on the effects of eggshell membrane dietary supplement

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000018888

Enrollment

Registered

2015-09-02

Start date

2015-09-02

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aging

Interventions

Oral intake of eggshell membrane contained supplements (During 3 months, 4 tablets in every morning and evening) Oral intake of eggshell membrane removed supplements (During 3 months, 4 tablets in eve

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Healthy males and females older than 20 years and younger than 65 years, 30 in total number

Exclusion criteria

Exclusion criteria: Persons suffering from diseases, persons who are taking-ingested drugs and foods to bring any influence on the experiment, persons who can not tolerate the experiment physically, smokers

Design outcomes

Primary

Measure	Time frame
Improvement of lung function, skin elasticity, and diversity of intestinal microflora after two months of taking eggshell membrane supplements.	—

Secondary

Measure	Time frame
Maximal oxygen uptake, standing posture, height, weight, BMI, dietary survey, heart rate, respiratory rate, walking speed, resting pulse, ventilatory work threshold, grip strength, blood cytokine hormone, blood test, urine test, sit-ups, psychological test, arterial stiffness, body composition, zigzag walk, back muscle strength, leg muscle strength, dustpan, repetitive lateral jump, long sit Body bending, long sit forward bending, liver stiffness, back skin elasticity, video recording, two-step test, information on lifestyle, arm skin moisture, oil, and transpiration, skin stratum corneum lipid profile measurement, and bone density measurement (all assessed before, 3 weeks, 4 weeks, 8 weeks, and 12 weeks after intake)	—

Measure

Time frame

Maximal oxygen uptake, standing posture, height, weight, BMI, dietary survey, heart rate, respiratory rate, walking speed, resting pulse, ventilatory work threshold, grip strength, blood cytokine hormone, blood test, urine test, sit-ups, psychological test, arterial stiffness, body composition, zigzag walk, back muscle strength, leg muscle strength, dustpan, repetitive lateral jump, long sit Body bending, long sit forward bending, liver stiffness, back skin elasticity, video recording, two-step test, information on lifestyle, arm skin moisture, oil, and transpiration, skin stratum corneum lipid profile measurement, and bone density measurement (all assessed before, 3 weeks, 4 weeks, 8 weeks, and 12 weeks after intake)

—

Countries

Japan

Contacts

Public ContactMiho Shimizu

Tokyo University of Agriculture and Technology Grad Sch of Eng, Dept of Appl Chem

mshmz@cc.tuat.ac.jp042-388-7539

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026

Foods with Function Claims: Empirical studies for &quot;Mibyo (presymptomatic state) prevention&quot;, &quot;Health Promotion&quot;, &quot;Become healthy&quot;, &quot;Can walk lightly&quot; and &quot;Rejuvenate&quot; by intake of eggshell membrane dietary supplement, TO-II BEAUTY EVOLUTION