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IOP-lowering effect lasting for 24 hours of Tapcom combination ophthalmic solution switched from Tapros ophthalmic solution 0.0015% and Timoptol XE Ophthalmic Solution 0.5%.

IOP-lowering effect lasting for 24 hours of Tapcom combination ophthalmic solution switched from Tapros ophthalmic solution 0.0015% and Timoptol XE Ophthalmic Solution 0.5%. - IOP-lowering effect lasting for 24 hours of Tapcom combination ophthalmic solution switched from Tapros ophthalmic solution 0.0015% and Timoptol XE Ophthalmic Solution 0.5%.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000018846
Enrollment
20
Registered
2015-08-29
Start date
2015-06-19
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

primary open angle glaucoma

Interventions

Sponsors

Nippon Medical School Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with unilateral or bilateral primary open angle glaucoma Patients who can visit the hospital according to the observation/test schedule determined in the study protocol

Exclusion criteria

Exclusion criteria: Patients with some corneal abnormality or other diseases which may interfere with accurate IOP measurement using Goldmann applanation tonometer Patients with a history of corneal refractive surgery Patients with active extraocular disease, inflammation or infection in the eye(s) or eyelid(s) Patients with allergy to the ingredients used in the present study Pregnant, lactating women or women who may be pregnant, and women who wish to be pregnant or can not conduct appropriate contraception during the study period Patients who are contraindicated to beta blockers (those who with bronchial asthma or insufficiently controlled heart failure)

Design outcomes

Primary

MeasureTime frame
Mean 24-hour IOP after the drug was administered for 8 weeks

Countries

Japan

Contacts

Public ContactKenji Nakamoto

Nippon Medical School Hospital Ophthalmology

makken45@nms.ac.jp03-3822-2131

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026