Pancreatic neuroendocrine tumor
Conditions
Interventions
Ethanol injection into the tumor by using EUS
Sponsors
Okayama University Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)The diagnosis of p-NET(G1 or G2) was confirmed by pathology from a core biopsy specimen obtained by EUS-FNA(WHO 2010 classification) 2)Low suitability for surgery(ASA grade>=3) or refusal of surgery 3)The p-NET within 2 cm in diameter by using CE-CT 4)The p-NET with non-function or insulinoma
Exclusion criteria
Exclusion criteria: 1)Severe allergy history against medical drug 2)Allergy for contrast medium 3)Allergy for ethanol 4)Cases that could not visualize or puncture by using EUS 5)Cases that were diagnosed NEC from a core biopsy specimen obtained by EUS-FNA(WHO2010 classification) 6)Located near the main pancreatic duct 7)PT<=50% or INR>=1.5 8)PLT<=50,000/uL 9)eGFR<=30 mL/min 10)Patients who administered more than 2 anti-thrombotic agent 11)Patients with performance status 2-4. 12)Patients with poor prognosis (less than 3-year) 13)Age<20 14)Patients without informed consent 15)Patients who are judged inappropriate by chief medical examiner
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Complete ablation rate (Treatment responses were assessed according to enhanced residual tumor areas on CE-CT) | — |
Countries
Japan
Contacts
Public ContactKazuyuki Matsumoto
Okayama University Hospital Department of Gastroenterology & Hepatology
Outcome results
None listed