Efficacy of flurbiprofen axetil as add-on therapy for postoperative pain after Total Knee Arthroplasty

Efficacy of flurbiprofen axetil as add-on therapy for postoperative pain after Total Knee Arthroplasty - Efficacy of flurbiprofen axetil as add-on therapy for postoperative pain after Total Knee Arthroplasty

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000018825

Enrollment

Registered

2015-09-01

Start date

2015-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

postoperative pain after Total Knee Arthroplasty (TKA)

Interventions

Administer flurbiprofen axetil after TKA Not administer flurbiprofen axetil after TKA

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patient who (is) / whose; 1) provides written informed consent. 2) over 65 year-old female 3) plans to have TKA for the first time at our hospital 4) is to be applied Vanguard RP type (BIOMET company) 5) FT(Femoral Tibial) angle is 180-190; before operation 6) HKA (Hip Knee Ankle) correction angle is less than 20; 7) Kellgren-Lawrence classification is grade 2-3

Exclusion criteria

Exclusion criteria: Patient who (is); 1) has disease that influences on the assessment of this study 2) considered difficult to perform assessment of this study by investigator. 3) has contraindications for medicine used in this study. 4) judged inappropriate for this study by investigator.

Design outcomes

Primary

Measure	Time frame
- pain score (during rest and during exercise) - other additional medication for postoperative pain	—

Countries

Japan

Contacts

Public ContactDaisuke Hashimoto

SOUSEIKAI Nishi-Kumamoto Hospital Nursing Department

nk-kansen@nishikuma.com096-358-1118

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026