COPD, interstitial pneumonia, neuromuscular disease
Conditions
Interventions
Pair of fine wire electrodes will be inserted, approximately 10 mm apart, into respiratory muscles (ie. parasternal intercostal muscle, transversus abdominis muscle, and so on) guided by high resoluti
Sponsors
Kitasato University
Eligibility
Sex/Gender
Male
Inclusion criteria
Inclusion criteria: healthy adult male subject.
Exclusion criteria
Exclusion criteria: Subjects who have history of pulmonary or cardiovascular or neuromuscular disorders were excluded. Subjects who have pointed out some abnormality by pre-study evaluation, including pulmonary function tests, electrocardiography and echocardiography.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| EMG activity of respiratory muscles (i.e. parasternal intercostal, external intercostal, transversus abdominis muscles and so on) obtained by fine wire electrodes. | — |
Secondary
| Measure | Time frame |
|---|---|
| Ventilatory parameters (i.e. inspiratory time (TI), expiratory time (TE), total time per breath (TT), frequency of respiration (f), tidal volume (VT) and minute ventilation (VI)), end-tidal CO2 (ETCO2), oxygen saturation values obtained from pulse oximetry (SpO2), and heart rate. | — |
Countries
Japan
Contacts
Public ContactMasanori Yokoba
School of Allied Health Sciences, Kitasato University/ Kitasato University Hospital Medical Laboratory Sciences/ Pulmonary Medicine
Outcome results
None listed