The patients who need gastroenterological surgery and were treated with prophylactic aspirin due to cardiovascular events
Conditions
Interventions
aspirin continuation
withdraw aspirin (alternative heparin)
Sponsors
Clinical Study Group of Osaka University, Risk Management Group
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) open- or laparoscopic- cholecystectomy, gastorectomy, or colo-rectal surgery. (2) more than 3 months aspirin use (3) PS 0-2 (4) written informed consent
Exclusion criteria
Exclusion criteria: (1) platelets < 15x10^4/uL (2) active or possible bleeding (3) active infection (4) anti-coagulant use (5) necessary of anti-coagulant for perioperative VTE prophylaxis (6) contraindication of intermittent pneumatic compression for VTE (7) severe complications (e.g. hepatic failure, uncontrollable hypertension, bronchial asthma) (8) allergy for aspirin or heparin (9) history of brain surgery (10) history of MI or angina (11) scheduled other surgery (12) pregnancy (13) mental disorder (14) others
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| operative blood loss | — |
Secondary
| Measure | Time frame |
|---|---|
| Adverse events with peri-operative hemorrhage, transfusion rate, re-operation rate, hospital stay, cardio-vasuluar/cardio-cerebrovascular events, delta hemoglobin | — |
Countries
Japan
Contacts
Public ContactShogo Kobayashi
Osaka University Department of Surgery
Outcome results
None listed