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Neoadjuvant chemotherapy of S-1/OXaliplatin for locally advanced Gastric cancer PII

Neoadjuvant chemotherapy of S-1/OXaliplatin for locally advanced Gastric cancer PII - Neo G-SOX PII study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000018661
Enrollment
40
Registered
2015-08-14
Start date
2015-08-14
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

gastric cancer

Interventions

Sponsors

Kobe City Medical Center General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1)histlogically proven gastric adenocarcinoma 2)Clinical T4, or T3 disease in cases of the schirrhous type including giant type 3 with a maximal diameter of more than 8 cm, bulky N2 confirmed by abdominal CT and laparoscopy. The T and N stages are determined according to the method proposed by Haberrmann. 3)Curative resection possible by total body computed tomography (CT) scan 4)Performance status must be Eastern Cooperative Oncology Group (ECOG) 0, or 1 5)Age >= 20 years 6)Patients who can take medication orally 7)Adequate bone marrow, hepatic, renal, cardiac and respiratory functions 8)Written informed consent

Exclusion criteria

Exclusion criteria: 1) active synchronous or metachronous malignancy other than carcinoma in situ 2) pregnant or nursing 3) severe mental disorders 4) uncontrolled diabetes mellitus 5) history of myocardial infarction, unstable angina within 3 months prior to the registration 6) serious coexisting illness 7) active infection 8) peripheral neuropathy greater than Grade 2 9) ileus 10) massive pleural effusion or ascites

Design outcomes

Primary

MeasureTime frame
curative resection rate

Countries

Japan

Contacts

Public ContactYoshihiro Okita

Kagawa University Hospital Department of Clinical Oncology

yokita@med.kagawa-u.ac.jp087-898-5111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026