1. Patinets taking anticoagulants because of thrombotic risk (CHADS2 score more than 2 or mechnical valve replacement) 2. Colorectal polyps more than 5mm in diameter 3. Within 3 polyps can be resected in one procedure 4. Over 20 years old 5. PS(ECOG)0, 1, 2 6. patients without severe anemia, moderate to severe thrombocytopenia, severe liver dysfunction and severe renal dysfunction
Conditions
Interventions
anticoagulant therapy
Sponsors
Division of Gastroenterology Teikyo University Chiba Medical Center
Shin-Tokyo Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients with anticoagulant therapy (CHADS2 score ). Colorectal polyps more than 5mm in diameter. Patients without severe anemia, moderate to severe thrombocytopenia, severe liver dysfunction and severe renal dysfunction. PS(ECOG) 0, 1, 2
Exclusion criteria
Exclusion criteria: Patients taking antithrombotic agents other than warfarin or NOAC. Patients taking NSAIDs and not able to interrupt 7 days before endoscopic therapy and 28 days after therapy. Female who are pregnant or lactating. Patients who have psychiatric disease. patients who have active bacterial infection or fungal infection. Patients with poor control hypertension(SBP more than 160mmHg or DBP more than 100mmHg). Patients with chronic lung disease who need continuous oxygen therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Lower gastrointestinal hemorrhage after endoscopic resetion | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemorrhage not related with endoscopic therapy, thrombotic complications, perforation, other complications. | — |
Countries
Japan
Contacts
Public ContactShigetaka Tounou
Teikyo University Chiba Medical Center Division of Gastroenterology
Outcome results
None listed