Pediatric Patients undergoing cardiac surgery
Conditions
Interventions
RIPC group: RIPC is induced after induction of anesthesia and before skin incision. Three 5-minute cycles of ischemia, achieved by inflation of a blood-pressure cuff to 30mmHg above the patient'
s systolic pressure, followed by 5-minute reperfusion while the cuff is deflated, are applied to the single leg.
Control group: In controls, the cuff was placed around the leg but not inflated.
Sponsors
Kanagawa children's medical center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Pediatric patients who are scheduled to undergo cardiovascular surgery with cardioplegic cardiac arrest under general anesthesia
Exclusion criteria
Exclusion criteria: Newborns of less than 38 weeks' gestation, children requiring mechanical ventilation, children at risk for transient limb ischemia, and children with severe heart failure using preoperative inotropic agents are excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative serum concentrations of troponin I(TnI) | — |
Secondary
| Measure | Time frame |
|---|---|
| Perioperative serum concentrations of lactate dehydrogenase (LDH), creatine kinase(CK), and its isoenzyme(CKMB) Inotropic score(IS) Mechanical ventilation time | — |
Countries
Japan
Contacts
Public ContactKyoko Yamauchi
Kanagawa children's medical center Department of Anesthesiology
Outcome results
None listed