therapeutic efficacy of ezetimibe and statins for vascular endothelial dysfunction by high-fat diet loadingin patients with type 2 diabetes

therapeutic efficacy of ezetimibe and statins for vascular endothelial dysfunction by high-fat diet loadingin patients with type 2 diabetes - Effects of ezetimibe on vascular endothelial dysfunction

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000018629

Enrollment

Registered

2015-08-10

Start date

2012-05-15

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Type 2 diabetes Hyperlipidemia

Interventions

ezetimibe subjects were allocated randomly by the envelope method to either of two treatment groups: ezetimibe 10 mg/day or rosuvastatin 2.5 mg/day. After 1-week oral administration of the allocated

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: The research participants were type 2 diabetes, aged between 20 and 79 years, who were not being treated for dyslipidemia, at the University of Occupational and Environmental Health, Department of Endocrinology, Metabolism and Diabetes and affiliated hospitals.

Exclusion criteria

Exclusion criteria: We excluded patients treated with insulin, and those with abnormalities in the electro-cardiogram.

Design outcomes

Primary

Measure	Time frame
The primary endpoint was the difference between RHI changes following treatment with each of the two drugs.	—

Countries

Japan

Contacts

Public ContactAkira Kurozumi

University of Occupational and Environmental Health First Department of Internal Medicine, School of Medicine

akira@med.uoeh-u.ac.jp093-603-1611

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026