depressive symptoms, mild memory problems
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Subject who fulfill the following all criteria (1) Independent adults aged 65 years and older living within the community (2) memory problems (a. or b.): a. objective mild memory decline (indicated by an age- and education-adjusted score at least 1.0 SDs below the reference threshold), b. subjective memory complaint (3) depressive symptoms (Geriatric Depression Scale >=5)
Exclusion criteria
Exclusion criteria: (1) dementia diagnosis (2) serious neurological or musculoskeletal diagnoses, such as Parkinson's disease, depression, and others (3) Mini-Mental State Examination score 18 and below (4) incapable of taking cognitive performance tests (5) contraindications of physical exercise (6) Use of walking aids in daily life
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| (1) depressive symptoms at post intervention (6 month) (2) memory performance at post intervention (6 month) | — |
Secondary
| Measure | Time frame |
|---|---|
| (1) cognitive function (attention, executive function, processing speed, etc.) (2) neuroimaging data (3) physical performance and physical activity (4) psychological outcomes (5) biomarker | — |
Countries
Japan
Contacts
National Center for Geriatrics and Gerontology Department of Preventive Gerontology