Skip to content

Study for Decreasing Depressive Symptoms and Increasing Memory Performance in the Elderly

Study for Decreasing Depressive Symptoms and Increasing Memory Performance in the Elderly - Effects of exercise and horticultural intervention on the brain and mental health in older adults with mild memory problems and depressive symptoms

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000018547
Enrollment
90
Registered
2015-08-07
Start date
2015-07-27
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

depressive symptoms, mild memory problems

Interventions

exercise group: once-weekly exercise program for 20 weeks horticultural group: once-weekly horticultural program for 20 weeks Control group: educational class

Sponsors

Department of Preventive Gerontology, National Center for Geriatrics and Gerontology
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Subject who fulfill the following all criteria (1) Independent adults aged 65 years and older living within the community (2) memory problems (a. or b.): a. objective mild memory decline (indicated by an age- and education-adjusted score at least 1.0 SDs below the reference threshold), b. subjective memory complaint (3) depressive symptoms (Geriatric Depression Scale >=5)

Exclusion criteria

Exclusion criteria: (1) dementia diagnosis (2) serious neurological or musculoskeletal diagnoses, such as Parkinson's disease, depression, and others (3) Mini-Mental State Examination score 18 and below (4) incapable of taking cognitive performance tests (5) contraindications of physical exercise (6) Use of walking aids in daily life

Design outcomes

Primary

MeasureTime frame
(1) depressive symptoms at post intervention (6 month) (2) memory performance at post intervention (6 month)

Secondary

MeasureTime frame
(1) cognitive function (attention, executive function, processing speed, etc.) (2) neuroimaging data (3) physical performance and physical activity (4) psychological outcomes (5) biomarker

Countries

Japan

Contacts

Public ContactHyuma Makizako

National Center for Geriatrics and Gerontology Department of Preventive Gerontology

makizako@ncgg.go.jp0562-46-2311

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026