Metastatic brain tumor Glioma Lymphoma
Conditions
Interventions
Sponsors
Tokushima university
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: Patients who meet all the following criteria can be included in the study: 1.Adult (20 years old or older) 2.Patients with brain tumor suspected (including necrosis, recurrence) 3.Written informed consent is obtained.
Exclusion criteria
Exclusion criteria: Patients who meet any of the following criteria are not eligible for the study: 1.Contraindication of MRI exam. Patients who have a heart pacemaker, cochlear implant, metallic foreign body, metallic devices 2.Patients who have history of hypersensitivity for Gd contrast media 3.Patients with severe CKD(eGFR<30mL/min/m2) 4.Pregnancy 5.Any others judged ineligible as a subject by the investigator
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Non-Inferiority of diagnostic concordance among high grade glioma, Lymphoma and Metastasis by ASL-MRI in comparison with DSC-MRI. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. Relationship between category based on discrepancy between ASL imaging and enhanced MR imaging, histological findings of brain tumors. 1. Category : "ASL dominant", and "CE dominant" 2. Diagnostic performance of recurrence and radionecrosis (in primary tumors) by ASL-MRI (Sensitivity, Specificity, PPV, NPV by quantitative evaluation) 3. Relationship between ASL(CBF ) and DSC(CBV, CBF, MTT, Tmax) parameters. | — |
Countries
Japan
Contacts
Public ContactTakashi Abe
Tokushima University Institute of Biomedical Sciences, School of Medicine
Outcome results
None listed