Cardiovascular prognostic coupling study in Japan

Cardiovascular prognostic coupling study in Japan - Cardiovascular prognostic coupling study in Japan(Coupling Registry)

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000018474

Enrollment

7000

Registered

2015-07-29

Start date

2015-07-29

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cardiovascular disease

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patient with at least one of the following cardiovascular risk factor: 1. Diabetes, glucose tolerance disorder 2. Dyslipidemia 3. high-normal normotension and grade I - III hypertension (>130/85 mmHg) 4. Current smoking 5. Renal disease (eGFR <= 60 or positive proteinuria) 6. Past history of cardiovascular disease (coronary artery disease, cerebrovascular disorder or non-cardiogenic cerebrovascular disorder, aortic dissection, peripheral artery disease, history of hospitalization by heart failure) 7. atrial fibrillation 8. Metabolic syndrome 9. Chronic obstructive pulmonary disease 10. Sleep apnea syndrome

Exclusion criteria

Exclusion criteria: 1. Patients with chronic renal failure in haemodialysis 2. Other seriously ill patients (e.g. end stage of cancer, active connective tissue disease) 3. Alcohol addiction 4. Drug addiction 5. Patients who cannot visit a hospital alone by walk 6. Patients who cannot give informed consent by themselves 7. Patients who are judged to be inappropriate for the study by physician

Design outcomes

Primary

Measure	Time frame
Time to major cardiovascular events. Major cardiovascular events; a composite of cerebral infarction, cerebral hemorrhage, subarachnoid hemorrhage, unknown type of stroke, myocardial infarction, cardiovascular intervention due to angina pectoris, and sudden death.	—

Secondary

Measure	Time frame
1. Time to various events onset. In addition to each component of major cardiovascular events, followings are considered as "various events": hospitalization by angina pectoris; hospitalization by heart failure, aortic dissection; occlusive arteriosclerosis; end stage renal insufficiency; doubling of serum creatinine values; new onset of atrial fibrillation; dementia; need of nursing care; total death. 2. Change in blood pressure 3. Increase of CAVI or ABI value. 4. Development of left ventricular hypertrophy 5. Adverse event	—

Measure

Time frame

1. Time to various events onset*. * In addition to each component of major cardiovascular events, followings are considered as "various events": hospitalization by angina pectoris; hospitalization by heart failure, aortic dissection; occlusive arteriosclerosis; end stage renal insufficiency; doubling of serum creatinine values; new onset of atrial fibrillation; dementia; need of nursing care; total death. 2. Change in blood pressure 3. Increase of CAVI or ABI value. 4. Development of left ventricular hypertrophy 5. Adverse event

—

Countries

Japan

Contacts

Public ContactKazuomi Kario

Jichi Medical University School of Division of Cardiovascular Medicine, Department of Medicine

coupling@jichi.ac.jp0285-58-7344

Outcome results