Effect of Subcutaneous Epinephrine/Saline/Local Anesthetic Versus Saline-Only Injection on Split-Thickness Skin Graft Donor Site

Effect of Subcutaneous Epinephrine/Saline/Local Anesthetic Versus Saline-Only Injection on Split-Thickness Skin Graft Donor Site - Effect of Tumescent Technique on Split-Thickness Skin Graft Donor Site

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000018448

Enrollment

140

Registered

2015-08-01

Start date

2014-05-21

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

split-thickness skin graft donor site

Interventions

Use tumescent technique before harvesting skin graft adrenaline application after graft harvesting

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.No skin disease in donor sites 2.Can get informed consent 3.Age 20-85 4.Size of the donor sites over 20 cm2

Exclusion criteria

Exclusion criteria: 1.Patients who do not conform inclusion criteria. 2.Decision by researchers

Design outcomes

Primary

Measure	Time frame
1.Healing time 2.post operative pain 3.ulcer recurrence 4.existence of hypertrophic scar	—

Countries

Japan

Contacts

Public ContactKohei Fukuoka

Tottori university hospital Department of plastic and reconstructive surgery

kfukuoka@med.tottori-u.ac.jp0859-38-6711

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026