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Observational study to evaluate clinical significance of coronary spasm in the culprit coronary artery in patients with acute myocardial infarction

Observational study to evaluate clinical significance of coronary spasm in the culprit coronary artery in patients with acute myocardial infarction - Observational study of coronary artery spasm after AMI

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000018432
Enrollment
800
Registered
2015-08-01
Start date
2005-09-20
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute myocardial infarction

Interventions

None listed

Sponsors

University of Yamanashi, Department of Internal Medicine II
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: The study patients, who admitted to Yamanashi University Hospital, met all of the following inclusion criteria; 1. Patients with acute myocardial infarction (AMI), who received emergent coronary angiography and successful reperfusion therapy by primary percutaneous coronary intervention using stent within 24 hrs after onset of AMI. 2. Provocation test for coronary spasm in the culprit coronary artery with acetylcholine at the discharge.

Exclusion criteria

Exclusion criteria: The study patients met the following exclusion criteria were excluded; 1. Residual organic stenosis > 50% in the culprit coronary artery; 2. Previous coronary artery bypass surgery; 3. Congestive heart failure at 1 week after AMI; 4. Valvular heart diseases, neoplasm, secondary hypertension, renal dysfunction (serum creatinine concentration > 2.0 mg/dL) or other serious diseases; 5. Left main trunk disease

Design outcomes

Primary

MeasureTime frame
Composite endpoints during 5 years after AMI; Cardiac death, non-fatal myocardial infarction, unstable angina requiring admission

Countries

Japan

Contacts

Public ContactKiyotaka Kugiyama

Yamanashi University Hospital Internal Medicine II

kugiyama@yamanashi.ac.jp055-273-9590

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026