Healthy adult
Conditions
Interventions
Ingestion of test food containing lactobacillus for 12 consecutive weeks
Ingestion of placebo without lactobacillus for 12 consecutive weeks
Sponsors
TTC Co., Ltd.
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Males and females from 20 to 64 years of age 2) A lower salivary secretory immunoglobulin A secretion rate
Exclusion criteria
Exclusion criteria: 1) Subjects who routinely use (more than 3 times a week) food or medicine containing of lactobacillus 2) Subjects routinely taking dietary supplements which may influence immune function 3) Subjects who has history of the allergic disease 4) Subjects who are under medication which may influence the outcome of the study (e.g., hyposensitization) 5) Subjects who are have treated oral or dental care within the last one month prior to the current study or are planned to treat oral or dental care 6) Subjects who has oral or dental problems with bleeding 7) Night and day shift worker or manual laborer 8) Subjects who has carries out an intense activity (e.g., marathon race) 9) Subjects who cannot carry out a procedure of various inspection by the rule during the study period 10) Subjects who has a disease under treatment or are judged to that medical treatment are necessary by the doctor 11) Subjects who has under treatment or a history of serious disease(e.g., diabetes, liver disease, kidney disease, or heart disease) and disease to affect the adrenal cortical hormone secretion 12) Subjects having possibilities for emerging allergy related to the study 13) Subjects who are judged as unsuitable for the study based on the results of clinical and physical examination on preliminary examination 14) Subjects who are planned to become pregnant after informed consent for the current study or are pregnant or lactating 15) Subjects who have participated in other clinical study within the last one month prior to the current study or are planned to participate in other clinical study after informed consent for the current study 16) Subjects who are judged as unsuitable for the study based on the results of lifestyle questionnaire 17) Subjects who are judged as unsuitable for the study by the investigator for other reason
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Salivary s-IgA secretion rate | — |
Secondary
| Measure | Time frame |
|---|---|
| Salivary s-IgA concentration | — |
Countries
Japan
Contacts
Public ContactHiroyasu Shimada
TTC Co., Ltd. Clinical Research Planning Department
Outcome results
None listed