Research of increased gas by lactulose load test in irritable bowel syndrome

Research of increased gas by lactulose load test in irritable bowel syndrome - Lactulose test for IBS and SIBO

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000018422

Enrollment

Registered

2015-07-25

Start date

2015-07-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

irritable bowel syndrome, small intestinal bacterial overgrowth

Interventions

The first group

lactulose 10g / 50kg load after 30 minutes to 120 minutes of observation. The second group

lactulose 13g / 50kg 240 minutes to 300 minutes of observation after load.

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: According to the Rome III criteria of IBS.

Exclusion criteria

Exclusion criteria: Person who suffering from organic diseases. (When disease is not healed).

Design outcomes

Primary

Measure	Time frame
Imaging is first performed in early morning after fasting. After ingestion of lactulose, 1-4 plain abdominal radiographs are taken for investigation of increased gas during the indicated timeframe. Regions of interest of the gas areas are highlighted on the images obtained. Gas images were divided into three areas, the stomach, small intestine, and large intestine, and each total area is calculated.	—

Measure

Time frame

Imaging is first performed in early morning after fasting. After ingestion of lactulose, 1-4 plain abdominal radiographs are taken for investigation of increased gas during the indicated timeframe. Regions of interest of the gas areas are highlighted on the images obtained. Gas images were divided into three areas, the stomach, small intestine, and large intestine, and each total area is calculated.

—

Secondary

Measure	Time frame
It is investigated the relationship between the symptoms and the gas of the amount which appears after lactulose load. By that relationship, it will determine whether it is possible to diagnosis of IBS and SIBO only a symptom of post-lactulose load.	—

Countries

Japan

Contacts

Public ContactYoshiharu Uno

Office Uno Column Editor

yoshiharu333@hotmail.com09069923113

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026