Does the pre-exercise ingestion of carbohydrate really cause transient hypoglycemia during exercise?

Does the pre-exercise ingestion of carbohydrate really cause transient hypoglycemia during exercise? - Pre-exercise ingestion of carbohydrate and transient hypoglycemia.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000018343

Enrollment

Registered

2015-08-01

Start date

2015-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

hypoglycemia

Interventions

Period: four days Factor A: glucose solution Factor B: breakfast intake Dose (factor A): 150g glucose Dose (factor B): 700kcal meal Time, frequency: once per experiment 150g glucose (no br

wash-out (1 week)&gt

150g glucose (eating breakfast)&gt

placebo (no breakfast)&gt

placebo (eating breakfast) Period: four days Factor A: glucose solution Factor B: breakfast intake Dose (factor A): 150g glucose Dose (factor B): 700kcal meal Time, frequency: once per experiment

150g glucose (no breakfast)&gt

wash-out(1 week)&gt

placebo (eating breakfast)&gt

placebo (no breakfast) Period: four days Factor A: glucose solution Factor B: breakfast intake Dose (factor A): 150g glucose Dose (factor B): 700kcal meal Time, frequency: once per experiment

150g glucose (eating breakfast) Period: four days Factor A: glucose solution Factor B: breakfast intake Dose (factor A): 150g glucose Dose (factor B): 700kcal meal Time, frequency: once per exper

Eligibility

Sex/Gender

Male

Inclusion criteria

Inclusion criteria: Endurance athletes Healthy men

Exclusion criteria

Exclusion criteria: Subject who could not perform exercise and/or who have chronic diseases

Design outcomes

Primary

Measure	Time frame
Plasma glucose concentration and serum insulin concentration (measured at 30 min before the start of exercise, just before the start of exercise, 15 min after the start of exercise, 30 min after the start of exercise, 60 min after the start of exercise, immediately after the endurance exercise performance test). Endurance exercise performance (measured at immediately after the 60 min exercise).	—

Secondary

Measure	Time frame
Serum free fatty acid concentration, serum glycerol concentration, blood lactate concentration, red blood cell count, hemoglobin concentration, hematocrit, white blood cell count and differential, serum interleukin-6 concentration, plasma catecholamine concentration and differential, serum cortisol concentration, serum growth hormone concentration (measured at 30 min before the start of exercise, just before the start of exercise, 15 min after the start of exercise, 30 min after the start of exercise, 60 min after the start of exercise, immediately after the endurance exercise performance test). Respiratory exchange ratio, rate of perceived exertion (measured at 15 min after the start of exercise, 30 min after the start of exercise, 45 min after the start of exercise. 60 min after the start of exercise).	—

Measure

Time frame

Serum free fatty acid concentration, serum glycerol concentration, blood lactate concentration, red blood cell count, hemoglobin concentration, hematocrit, white blood cell count and differential, serum interleukin-6 concentration, plasma catecholamine concentration and differential, serum cortisol concentration, serum growth hormone concentration (measured at 30 min before the start of exercise, just before the start of exercise, 15 min after the start of exercise, 30 min after the start of exercise, 60 min after the start of exercise, immediately after the endurance exercise performance test). Respiratory exchange ratio, rate of perceived exertion (measured at 15 min after the start of exercise, 30 min after the start of exercise, 45 min after the start of exercise. 60 min after the start of exercise).

—

Countries

Japan

Contacts

Public ContactKumpei Tanisawa

Waseda University Faculty of Sport Sciences

Kunpei-tanisawa@fuji.waseda.jp04-2947-6833

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026