The analysis of treatment-related leukemia after taxan and platinum based chemotherapy, retrospective multicenter study.

The analysis of treatment-related leukemia after taxan and platinum based chemotherapy, retrospective multicenter study. - The analysis of treatment-related leukemia after taxan and platinum based chemotherapy, retrospective multicenter study.

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000018329

Enrollment

5000

Registered

2015-08-01

Start date

2015-06-08

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gynecologic malignancies

Interventions

None listed

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients with pathologically confirmed ovarian cancer, uterine body cancer, cervical cancer. Patients provided taxan and Pt based chemotherapy from January, 2002 to December, 2006. When taxan and Pt based chemotherapy was provided as neo adjuvant chemotherapy, it applies. Patients without medical history of malignancies before taxan and Pt based chemotherapy. Patients provided only taxan and Pt based chemotherapy.

Exclusion criteria

Exclusion criteria: Patients with radiation therapy.

Design outcomes

Primary

Measure	Time frame
Incidence of treatment-related leukemia after only taxan and platinum(Pt) based chemotherapy.	—

Secondary

Measure	Time frame
Incidence of TRL according to the combination of Taxan and Pt. Relationship of total dose of Taxan and the Pt and the incidence of TRL. Duration from the last chemotherapy to the TRL. Characteristics of chromosomal abnormality and karyo -type of TRL. Treatment and outcome of TRL.	—

Countries

Japan

Contacts

Public ContactManabu Sakurai

University of Tsukuba , Faculty of Medicine Department of Obstetrics and Gynecology

m-sakurai@md.tsukuba.ac.jp029-853-3073

Outcome results