Effects of Pycnogenol chewing gum on oral malodor, gingivitis and plaque formation

Effects of Pycnogenol chewing gum on oral malodor, gingivitis and plaque formation - Effects of Pycnogenol chewing gum on oral health

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000018305

Enrollment

Registered

2015-07-14

Start date

2011-11-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

oral malodor, gingivitis, periodontitis

Interventions

The subjects were instructed to chew 2 pieces of pycnogenol gum (5 mg) 6 times daily for 15 min during the intake period (4 weeks). The subjects were instructed to chew 2 pieces of pycnogenol gum (1

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: participant without systemic diseases

Exclusion criteria

Exclusion criteria: under dental treatment antibacterial therapy within the previous 30 days smoker

Design outcomes

Primary

Measure	Time frame
Reduction of oral malodor, plaque formation and improvement of gingivitis at baseline, 2 weeks and 4 weeksr	—

Countries

Japan

Contacts

Public ContactKiyoko Watanabe

Kanagawa Dental University Department of Microbiology

watanabe@kdu.ac.jp+81-46-822-8867

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026