Effects of denosumab on bones in patients with cementless total hip arthroplasty

Effects of denosumab on bones in patients with cementless total hip arthroplasty - Effects of denosumab on bones in patients with cementless total hip arthroplasty

Status

Recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000018260

Enrollment

100

Registered

2015-07-10

Start date

2015-07-10

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Total hip arthroplasty

Interventions

Denosumab injection

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Unilateral cementless total hip arthroplasty More than 6 months after the operation

Exclusion criteria

Exclusion criteria: Hypocalcemia Severe renal dysfunction Previous treatment using denosumab, bisphosphonates or teriparatide Previous treatment using other osteoporosis drugs during the past 6 months Diseases or treatments associated with bone metabolism Plan for invasive dental treatment

Design outcomes

Primary

Measure	Time frame
Bone mineral density Bone metabolism markers Nutrient intake Physical activity	—

Countries

Japan

Contacts

Public ContactKeisuke Watarai

Saitama Medical University Department of Orthopaedic Surgery

kwatarai@saitama-med.ac.jp049-276-1238

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026