multicentric cohort study for acute encephalopathy with biphasic seizures and late reduced diffusion

multicentric cohort study for acute encephalopathy with biphasic seizures and late reduced diffusion - registry-AESD

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000018259

Enrollment

150

Registered

2015-07-15

Start date

2014-09-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

acute encephalopathy with biphasic seizures and late reduced diffusion (AESD)

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: patients who presented first and second phase (biphasic) seizures: 1) seizures during febrile (37.5 degrees C or higher) illness (first phase seizures) 2) secondary seizures with 24-hour or longer interval after first phase seizures (second phase seizures)

Exclusion criteria

Exclusion criteria: 1) biphasic seizures induced by the disorders other than AESD, e.g., meningitis/encephalitis caused by pathogenic organism or immunological mechanism, other types of acute encephalopathies, epileptic seizures, disorders by unknown etiology but obviously different from AESD 2) judged as inappropriate for this study by investigators

Design outcomes

Primary

Measure	Time frame
changes of the rate of patients with score 1 and 2 by Pediatric Cerebral Performance Category Scale (PCPC scale)	—

Secondary

Measure	Time frame
surveillance of current therapeutic regimen for AESD	—

Countries

Japan

Contacts

Public ContactYuri Sakaguchi

Tokyo Metropolitan Children's Medical Center Division of Neurology

sn_AESD@tmhp.jp042-300-5111

Outcome results