Observational study to evaluate effectiveness of prophylactic cranial irradiation on patients with limited-stage small cell lung cancer.

Observational study to evaluate effectiveness of prophylactic cranial irradiation on patients with limited-stage small cell lung cancer. - Observational study of PCI on LS-SCLC

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000018253

Enrollment

Registered

2015-07-16

Start date

2015-07-14

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Limited-stage small cell lung cancer

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Histologically or cytologically confirmed small cell lung cancer in limited-stage (IA to IIIB) 2. Responded to first treatment to complete response or good partial response (short axis of all mediastinal lymphnodes <15mm, no persisting primary lesion) 3. Confirmed absence of brain metastasis with enhanced cranial MRI within 2 months after the finish of initial treatment

Exclusion criteria

Exclusion criteria: 1. Patients with brain metastasis 2. Patients judged as inappropriate for this study by investigators

Design outcomes

Primary

Measure	Time frame
Incidence of brain metastasis	—

Secondary

Measure	Time frame
Overall survival time, Quality of life (QCQ-C30/BN20), cognitive ability (MMSE)	—

Countries

Japan

Contacts

Public Contactkoji Nishimoto

Hamamatsu Univ. School of Medicine Department of Internal Medicine, second division

knishi@hama-med.ac.jp053-435-2263

Outcome results