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Exploratory study on the effects of antimicrobial therapy for refractory uveitis due to sarcoidosis.

Exploratory study on the effects of antimicrobial therapy for refractory uveitis due to sarcoidosis. - Antimicrobial therapy for uveitis due to sarcoidosis.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000018247
Enrollment
10
Registered
2015-07-15
Start date
2019-02-28
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sarcoidosis

Interventions

Oral administration of antibiotics.

Sponsors

Tokyo medical and dental university
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) age between 20 and 80 years old. 2) from whom written informed consent could be obtained. 3) Being diagnosed as sarcoidosis, and having active intermediate or posterior uveitis. 4) satisfy more than one of the followings: a) having grade one or more vitreous opacity b) having retinal phlebitis that could be detected by fluorescein angiography. c) having retinal yellow-white lesions that could be recorded by funds photograph.

Exclusion criteria

Exclusion criteria: satisfy one of the following: 1) having abnormal values by complete blood cell count. 2) having liver or kidney dysfunction. 3) having systemic infectious diseases such as active tuberculosis, hepatitis B, hepatitis C, or syphilis. 4) being allergenic against clarithromycin or minocyclin. 5) those who researcher consider to be not eligible for the study.

Design outcomes

Primary

MeasureTime frame
Recurrence or exacerbation of ocular inflammation.

Countries

Japan

Contacts

Public ContactHiroshi Takase

Tokyo medical and dental university Ophthalmology

h.takase.oph@tmd.ac.jp03-3813-6111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026