Analysis of bacterial flora in the progression of chronic lower respiratory tract infection using 16S rRNA gene

Analysis of bacterial flora in the progression of chronic lower respiratory tract infection using 16S rRNA gene - Analysis of Chronic LRTI using 16S rRNA gene

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000018234

Enrollment

Registered

2015-07-07

Start date

2015-07-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients with suspected nontuberculous mycobacteria

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Patients 20 years of age and older 2. Patients with suspected NTM

Exclusion criteria

Exclusion criteria: 1. Patients without written informed consent to participate in this study 2. Patients with at risk of performing bronchoscopy, or without informed consent to perform bronchoscpy

Design outcomes

Primary

Measure	Time frame
Scores of periodical findings of chest high-resolution computed tomography.	—

Secondary

Measure	Time frame
1. Symptoms, laboratory data, spirometry 2. Bacteriological efficacy: sputum culture, and bacterial floral analysis findings of bronchoalveolar lavage fluid (BALF) with 16S ribosomal RNA gene sequencing. 3. Cytokines, chemokines and oxidative stress markers in BALF 4. Analysis of mineral components in BALF	—

Countries

Japan

Contacts

Public ContactKei Yamasaki

University of Occupational and Environmental Health, Japan Department of Respiratory Medicine

kkyamsaki1019@yahoo.co.jp093-603-1611

Outcome results