coronary artery disease
Conditions
Interventions
None listed
Sponsors
Department of Cardiovascular Medicine, Hokkaido University Graduate School of Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients with suspected or known stable coronary artery disease (CAD) who regularly visits 4 Japanese study sites are eligible. 2. Patients 20 years of age and older are eligible. 3. All patients receive from physicians the information necessary to give informed consent in writing to receive O-15 water positron emission tomography/computed tomography. Four Japanese study sites are as follows: Hokkaido University Hospital, Sapporo City General Hospital, ShinSapporo Hospital of Cardiology, Keiwakai Ebetsu Hospital
Exclusion criteria
Exclusion criteria: Exclusion criteria in patients' eligibility are described below. 1. Patients with a history of advanced atrioventricular block 2. Patients with bronchial asthma 3. Patients with suspected or known pregnancy 4. Patients who cannot give written consent 5. Patients who contact persons judge as ineligible for this study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Rest myocardial blood flow (MBF), stress MBF, and coronary flow reserve by quantitative O-15 water positron emission tomography/computed tomography between pre- and post-treatment in patients with coronary artery disease. | — |
Secondary
| Measure | Time frame |
|---|---|
| The prespecified secondary outcomes of the study are described below. 1. To assess predictors of improvement in CFR 2. To assess predictors of CFR at baseline | — |
Countries
Japan
Contacts
Public ContactMasanao Naya
Hokkaido University Graduate School of Medicine Department of Cardiovascular Medicine
Outcome results
None listed