Examination of having T790M or not after the EGFR-TKI tolerance in the EGFR gene variation-positive progress non-small-cell lung cancer

Examination of having T790M or not after the EGFR-TKI tolerance in the EGFR gene variation-positive progress non-small-cell lung cancer - Examination of having T790M or not after the EGFR-TKI tolerance in the EGFR gene variation-positive progress non-small-cell lung cancer

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000018150

Enrollment

Registered

2015-07-01

Start date

2014-08-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Non-Small-Cell Lung Cancer

Interventions

Examination with bronchoscope and CT-guided needle biopsy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Histologically or cytologically proven non-small cell lung cancer 2.After EGFR gene variation was positive and EGFR-TKI was effective, a condition progressed

Exclusion criteria

Exclusion criteria: 1.Serious medical complications 2.uncontrolled angina pectoris,myocardial infarction within 3 months, heart failure. 3.serious infectious diseases 4.Other clinical difficulties to this study

Design outcomes

Primary

Measure	Time frame
Having gene variation or not	—

Secondary

Measure	Time frame
Response rate	—

Countries

Japan

Contacts

Public ContactMidori Shimada

Nagasaki University Hospital Second Department of Internal Medicine

dear_tm_1016_612@yahoo.co.jp095-819-7273

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026