Effectiveness and safety of bronchial thermoplasty in the treatment with severe persistent bronchial asthma

Effectiveness and safety of bronchial thermoplasty in the treatment with severe persistent bronchial asthma - Effectiveness and safety of bronchial thermoplasty in patients with severe asthma

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000018140

Enrollment

Registered

2015-06-30

Start date

2015-06-30

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Bronchial asthma

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Uncontrolled severe asthma patients treated with high dose inhaled corticosteroid and long acting beta 2 agonists 2.Eligible for fiberoptic bronchoscopy

Exclusion criteria

Exclusion criteria: 1.Have a pacemaker, internal defibrillator, or other implantable electronic device. 2.Have a known sensitivity to medications required to perform bronchoscopy, including lidocaine, atropine, and benzodiazepines. 3.Have been previously treated with BT 4.Active respiratory infection 5.Asthma exacerbation or changing dose of systemic corticosteroids for asthma (up or down) in the past 14 days 6.Known coagulopathy. As with other bronchoscopic procedures, patients should stop taking anticoagulants, antiplatelet agents, aspirin, and NSAIDS before the procedure with physician guidance

Design outcomes

Primary

Measure	Time frame
Asthma exacerbation	—

Secondary

Measure	Time frame
Asthma control Pulmonary function QOL Bronchial wall thickness, diameter Adverse events	—

Countries

Japan

Contacts

Public ContactMotoyasu Iikura

National Center for Global Health and Medicine Respiratory Medicine

iikura-tky@umin.ac.jp03-3202-7181

Outcome results