Prospective study of efficacy and safety of Radiotherapy in combination with KORTUC for Breast Cancer.

Prospective study of efficacy and safety of Radiotherapy in combination with KORTUC for Breast Cancer. - Prospective study of efficacy and safety of Radiotherapy in combination with KORTUC for Breast Cancer.

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000018131

Enrollment

Registered

2015-07-01

Start date

2015-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

breast cancer

Interventions

Radiotherapy in combination with KORTUCII

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1)pathologically proven breast cancer 2)stage I-IIIA 3)received an explanation from the specialist about the advantages and disadvantages of surgery 4)Not suitable for surgery or refused surgery 5) Suitable for radiotherapy 6) Suitable for injecting the KORTUC to the tumor 7)PS is 0-2 8)Written informed consent

Exclusion criteria

Exclusion criteria: 1)prior history of radiation therapy in the thoracic. 2)Severe complication 3)History of hypersensitivity to hyaluronic acid 4)History of hypersensitivity to lidocaine hydrochloride 5)History of hypersensitivity to H2O2 6)investigator judged ineligible

Design outcomes

Primary

Measure	Time frame
Response rate local control rate	—

Secondary

Measure	Time frame
Progression free survival (PFS), Overall survival (OS), safty profile	—

Countries

Japan

Contacts

Public ContactHideki Nishimura

Kobe Minimally Invasive Cancer Center Department of Radiation Oncology

nishimura@k-mcc.net+81-78-304-0046

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026