Selection of The Target Population to Evaluate the Effect of Functional Foods with Regard to the Amelioration of Pollinosis Caused by Japanese White Birch (Betula platyphylla var. japonica)

Selection of The Target Population to Evaluate the Effect of Functional Foods with Regard to the Amelioration of Pollinosis Caused by Japanese White Birch (Betula platyphylla var. japonica) - A Preliminary Research for The Ameliorating Effect for White Birch Pollinosis by A Functional Food

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000018124

Enrollment

200

Registered

2015-06-29

Start date

2015-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Japanese white birch pollinosis

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. Subjects who have symptoms of pollinosis in the last 2 years. 2. Subjects who accept allergy tests of white birch pollen (collecting blood and skin prick test). 3. Subjects who agree to participate in the current study with a written informed consent.

Exclusion criteria

Exclusion criteria: 1. Subjects with serious cerebrovascular, cardiac, hepatic, renal and / or endocrine and metabolic disorders, or affected with infectious diseases requiring report to the authorities. 2. Subjects who have a history of gastrectomy, gastrorrhaphy, enterectomy and/ or other serious gastrointestinal surgeries. 3. Subjects who have a serious anemia. 4. Subjects who have a history of serious allergic reactions (anaphylaxis, etc.). 5. Subject who have sinusitis, nasal polyp, hypertrophic rhinitis, more than moderate chronic nasal inflammation, severe nasal septum deviation, etc. 6. Subjects who have bronchial asthma 7. Subject who are under immunotherapy such as allergen- specific desensitization. 8. Heavy smokers, alcohol addicts or subjects with irregular lifestyle. 9. Subjects who donated either 400ml whole blood within 12 weeks or 200ml whole blood within 4 weeks or blood components within 2 weeks prior to this study. 10. Pregnant or lactating women or women expect to be pregnant during the clinical trial. 11. Subjects who participated in other clinical trials within the last one month prior to the clinical trial. 12. Any other medical reasons judged by the doctor in charge.

Design outcomes

Primary

Measure	Time frame
Total IgE, White birch-specific IgE, skin prick test, questionnaires for pollinosis symptoms	—

Countries

Japan

Contacts

Public ContactDir. Prof. Jun NISHIHIRA, M.D., Ph.D.

Hokkaido Information University Health Information Science Center

nishihira@do-johodai.ac.jp011-385-4430

Outcome results