The effect of tranexamic acid on blood loss in bimaxillary orthognathic surgery.

The effect of tranexamic acid on blood loss in bimaxillary orthognathic surgery. - The effect of tranexamic acid on blood loss in bimaxillary orthognathic surgery.

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000018115

Enrollment

Registered

2015-07-01

Start date

2015-07-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Jaw defomities

Interventions

A loading dose of 20mg/kg of tranexamic acid in infused intravenously before Le Fort 1 osteotomy. A loading dose of 10mg/kg of tranexamic acid in infused intravenously before Le Fort 1 osteotomy and s

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients older than 16 years old and undergoing orthognathic surgery agoreed to participate in this traial.

Exclusion criteria

Exclusion criteria: Exclusion criteria are atrial fibrillation, coronary artery disease treated with drug eluting stent, severe choronic renal failure, congenital or acquried thrombophillia, and known or suspected allergy to tranexamic acid.

Design outcomes

Primary

Measure	Time frame
intraoperative blood loss	—

Countries

Japan

Contacts

Public ContactHideki Ichikawa

Tokyo Metropolitan Ohtsuka Hospital Depertment of Stomatology

hideki_ichikawa@tmhp.jp03-3941-3211

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026