Influence of female sex hormone change during menstrual cycle on propofol pharmacokinetics and pharmacodynamics

Influence of female sex hormone change during menstrual cycle on propofol pharmacokinetics and pharmacodynamics - influence of female menstrual cycle on propofol pharmacokinetics and pharmacodynamics

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000018109

Enrollment

Registered

2015-06-26

Start date

2015-06-26

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Patients planning on getting surgery under general anesthesia

Interventions

None listed

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: 1.Female patients planning surgery under general anesthesia 2.Patients who are able to provide written informed consent

Exclusion criteria

Exclusion criteria: 1.Obesity 2.Pregnant women and nursing mothers 3.Postmenopausal women 4.Patients with severe liver or kidney disorder 5.Patients with neurological disorder 6.Patients taking psychotropic drugs orally 7.Patients with hypersensitivity to propofol 8.Patients who attending physicians consider to be inappropriate due to other reasons mentioned above

Design outcomes

Primary

Measure	Time frame
preparation of pharmacokinetic/pharmacodynamic model on female surgical patients	—

Countries

Japan

Contacts

Public ContactAtsuko Tomita

National Defense Medical College Anesthesiology

con155@ndmc.ac.jp0429-95-1511

Outcome results