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Minimal dose oral cephalosporin regimen(MDC regimen), a new empiric therapy for the treatment of uncomplicated cystitis in women during the era of an increasing prevalence of drug-resistant pathogens.

Minimal dose oral cephalosporin regimen(MDC regimen), a new empiric therapy for the treatment of uncomplicated cystitis in women during the era of an increasing prevalence of drug-resistant pathogens. - Minimal-dose cephalosporinregimen(MDC regimen) for the treatment of female uncomplicated cystitis.

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000018071
Enrollment
100
Registered
2015-07-10
Start date
2005-04-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Acute uncomplicated cystitis in wpmen.

Interventions

Prescriibe 40mg cefaclor/day for a week that is divided in two doses onto empty stomch.

Sponsors

Yorio Naide
Lead Sponsor
Department of Infectious Diseases, School of Medicine, Keio University Department of Infectious Diseases, School of Medicine, Kitasato University
Collaborator

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Sexually active women or older, including women after climacterium.

Exclusion criteria

Exclusion criteria: Patients who have strucural of functional abnormality in the urinary tract.

Design outcomes

Primary

MeasureTime frame
Promptly getting asymptomatic and pyuria is cleared, and pathogens are eradicated from urine in a week, and no recurrence during the long term preventive treatment in the patients having suffered frequent recurrence.

Secondary

MeasureTime frame
No association of untoward reaction such as gastric symptom and anaphylactic reaction. Further, no recurrence with drug resistant pathogen during the long term treatment for prevention of frequent recurrence.

Countries

Japan

Contacts

Public ContactYorio Naide

Hannnou Seiwa Hospital Consultant

yorio823@jcom.home.ne.jp+81-42-974-2311

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026