A role of gut microbiota in the pathogenesis of gastrointestinal and liver diseases and the clinical application

A role of gut microbiota in the pathogenesis of gastrointestinal and liver diseases and the clinical application - A role of gut microbiota in the pathogenesis of gastrointestinal and liver diseases

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000018068

Enrollment

260

Registered

2015-06-24

Start date

2015-06-24

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

1)Nonalcoholic steatohepatitis (NASH) 2)Alcoholic hepatitis (ASH) 3)Liver cirrhosis due to NASH, ASH, viral hepatitis, Autoimmune hepatitis , Primary biliary cirrhosis, and Primary sclerosing cholangitis 4)Hepatocellular carcinoma 5)Ulcerative colitis 6)Crohn&#39

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients who meets each diagnostic criteria.

Exclusion criteria

Exclusion criteria: 1)Patients seropositive for HIV and/or syphilis 2)Patients treated with antibiotics within 1M 3)Patients under treatment with immunosuppressive therapy and/or chemotherapy 4)Patients in poor general condition

Design outcomes

Primary

Measure	Time frame
A comprehensive analysis of microbiota in feces derived from patients	—

Secondary

Measure	Time frame
A reproducibility of diseases by fecal microbiota transplantation of feces derived from patients to germ free mice	—

Countries

Japan

Contacts

Public ContactNobuhiro Nakamoto

Keio University School of Medicine Division of Gastroenterology and Hepatology, Department of Internal Medicine

nobuhiro@z2.keio.jp03-3353-1211

Outcome results