Localization of specialized intestinal metaplasia and the molecular alterations in Barrett's esophagus in a Japanese population: an analysis of biopsy samples based on the "Seattle" biopsy protocol

Localization of specialized intestinal metaplasia and the molecular alterations in Barrett's esophagus in a Japanese population: an analysis of biopsy samples based on the "Seattle" biopsy protocol - Phenotypic and molecular localization of BE

Status

Active, not recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000017994

Enrollment

Registered

2015-06-21

Start date

2014-08-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Barrett&#39

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with Barrett's esophagus with more than 1 cm in diameter by endoscopy

Exclusion criteria

Exclusion criteria: (1) Patients with a history of esophagectomy or gastrectomy (2) Patients having no application to the guidelines for gastroenterological endoscopy in patients undergoing antithrombotic treatment from Japan Gastroenterological Endoscopy Society (3) Patients who have determined by the physicians to have any reasons of unqualified

Design outcomes

Primary

Measure	Time frame
To investigate the differences of molecular alterations related to carcinogenesis using four-quadrant biopsies based on the "Seattle" biopsy protocol	—

Secondary

Measure	Time frame
To investigate the differences of molecular alterations related to carcinogenesis between specialized intestinal metaplasia and columnar lined epithelium in Barrett's esophagus (BE)	—

Countries

Japan

Contacts

Public ContactJiro Watari

Hyogo College of Medicine Division of Gastroenterology

watarij@hyo-med.ac.jp0798-45-6662

Outcome results