Effects of anesthetics on depression after modified electroconvulsive treatment

Effects of anesthetics on depression after modified electroconvulsive treatment - ECT a cross-over test

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000017924

Enrollment

Registered

2015-07-06

Start date

2016-07-07

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

severe depression

Interventions

GroupA) Propofol is used in the former half of the period and ketamine is used in the latter half of the period, during ECT procedure. GroupB) Ketamine is used in the former half of the period and p

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: severe depression

Exclusion criteria

Exclusion criteria: 1)Patients with mandatory admission 2)ECT procedure with other procedure 3)Patients with severe coronary artery disease or cerebrovascular disease 4)Severe liver dysfunction 5)Patients with hemodialysis 6)Patients with a permanent pacemaker 7)BMI(Body Mass Index) more than 35 or equal to 35 8)The patient involved in other randomized trail using drugs 9)Patients who were judged as inappropriate by doctors working for this trail

Design outcomes

Primary

Measure	Time frame
HAM-D((Hamilton depression score)	—

Secondary

Measure	Time frame
Pupil diameter measurement Hear rate viriability	—

Countries

Japan

Contacts

Public ContactJunko Nakahira

Osaka Medical College Department of Anestheisology

ane052@osaka-med.ac.jp072-683-1221

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026