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Phase II study of dynamic tumor tracking stereotactic body radiotherapy for liver cancer.

Phase II study of dynamic tumor tracking stereotactic body radiotherapy for liver cancer. - Phase II study of dynamic tumor tracking stereotactic body radiotherapy for liver cancer.

Status
Active, not recruiting
Phases
Phase 2
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000017886
Enrollment
48
Registered
2015-07-01
Start date
2015-07-24
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

liver cancer

Interventions

Radiotherapy

Sponsors

Kyoto University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1)Clinically diagnosed primary or metastatic liver cancers less than 4, and with diameter between 1 to 5 cm. 2) No indication or refusal for surgical resection, radio frequency ablation. 4) ECOG Performance Status 0-2 5) The patients can raise their arms and keep supine position with about 30 minutes. 6) Respiratory movement is more than 10mm. 7) Written informed consent

Exclusion criteria

Exclusion criteria: 1) History of radiation therapy to the site 2) Refractory pleural effusion or ascites 3) Esophageal varies with high risk of bleeding 4) Obviously active interstitial pneumonia or pulmonary fibrosis 5) Severe diabetes or collagen disease 6) Pregnant and lactating females 7) Severe mental disorder to participate in this study 8) Patients who are concluded to be inappropriate to participate in this study by their physicians

Design outcomes

Primary

MeasureTime frame
2-year local control rate

Secondary

MeasureTime frame
overall survival rate, progression free survival rate, local progression free survival rate, adverse event, severe adverse event, treatment accuracy, dose-volume index.

Countries

Japan

Contacts

Public ContactYukinori Matsuo

Kyoto University Department of Radiation Oncology and Image-applied Therapy, Graduate School of Medicine

ymatsuo@kuhp.kyoto-u.ac.jp075-751-3762

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026