Healthy volunteer,late onset psychosis
Conditions
Interventions
PET/MRI/neuropsychological batteries/neurological examinations
PET/MRI/neuropsychological batteries/neurological examinations
Sponsors
National Institute of Radiological Sciences
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: I. Patients 40 y.o.<=Age<=88 y.o. patients of late onset psychosis. II.Healthy volunteers 40 y.o.<=Age<=88 y.o., normal subjects
Exclusion criteria
Exclusion criteria: I. Patients 1. Subjects without ability to make informed consent 2. Subjects with any psychiatric disorder not due to late onset psychosis 3. Subjects with any organic brain disorder 4. Subjects with severe physical complication 5. Subjects with severe claustrophobia 6. Pregnant women 7. Subjects who was considered to be inappropriate to participate in the study II. Healthy volunteers 1. Subjects without ability to make informed consent 2. Subjects with any psychiatric disorder 3. Subjects with any organic brain disorder 4. Subjects with severe physical complication 5. Subjects with severe claustrophobia 6. Subjects who has participated in other study in recent 6 months. 7. Pregnant women 8. Subjects with tattoo 9. Subjects with metallic medical device in the body 10. Subjects who was considered to be inappropriate to participate in the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Distribution volume and binding potential measured by positron emission tomography with [11C]PBB3 | — |
Secondary
| Measure | Time frame |
|---|---|
| Difference of spatial distribution of [11C]PBB3 and [11C]PIB Correlations between tau deposition and various clinical scales | — |
Countries
Japan
Contacts
Public ContactKeisuke Takahata
National Institute of Radiological Sciences Molecular Imaging Center
Outcome results
None listed