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Longitudinal Changes of Salivary Oxytocin and Salivary Cortisol after Inhalation of Clary Sage Essential Oil Vapors: Preliminary Study

Longitudinal Changes of Salivary Oxytocin and Salivary Cortisol after Inhalation of Clary Sage Essential Oil Vapors: Preliminary Study - Longitudinal changes of Oxytocin after Clary Sage Oil

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000017830
Enrollment
10
Registered
2015-06-08
Start date
2015-06-09
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pregnant women between 38 and 40 weeks of gestation

Interventions

Interventions: Vapor bubbles are produced from clary sage essential oil dissolved in propylene glycol by an air pump. Subjects inhale the vapor for 20 minutes through a tube and funnel near their nos

Sponsors

St. Luke's International University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Low risk singleton pregnant women who are 38 weeks of gestation through 40 weeks of gestation 2. Plan to give birth with spontaneous delivery 3. Before the onset of labor 4. Asian and can read and write Japanese

Exclusion criteria

Exclusion criteria: 1. Experienced prolonged pregnancy 2. Previous caesarian section 3. Recurrent miscarriages (3 consecutive) 4. Medical history of treatment of infertility 5. Planned induced labor or cesarean section 6. Planned analgesia 7. Smokes tobacco 8. Alcoholic 9. Complications of pregnancy 10. Takes medication not to related to gestation 11. Hospital visits for complication not related to gestation 12. Medical history that needs treatment or follow up 13. Some allergies of food or drug 14. Plant allergy or allergic symptoms with aromatherapy 15. Breast feeding child 16. Olfactory disorder

Design outcomes

Primary

MeasureTime frame
Salivary oxytocin 10 minutes before intervention and 15, 30, 60 minutes after intervention

Secondary

MeasureTime frame
Salivary cortisol 10 minutes before intervention and 15, 30, 60 minutes after intervention, Polymorphisms of oxytocin receptor

Countries

Japan

Contacts

Public ContactYuriko Tadokoro

St. Luke's International University, Postgraduate School Nursing science, Women's Health & Midwifery

14dn011@slcn.ac.jp03-6226-6361

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026