Non-small cell lung cancer
Conditions
Interventions
Chemotherapy and IMRT
Sponsors
Shizuoka Cancer Center
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1) Histologically or cytologically confirmed NSCLC 2) Inoperable 3) Stage III NSCLC patients who are suitable for definitive RT 4) No previous chemotherapy and thoracic radiotherapy 5) Who have measurable lesions 6) Age 20-74 years old 7) Performance status 0,1 8) Who are able to eat by oral intake 9) Who are without severe co-morbid conditions 10) Informed consent
Exclusion criteria
Exclusion criteria: 1)Active double cancer 2)History of severe infections or complications 3)HBs antigen positive 4)History of thoracic radiotherapy 5)Radiographically (chest CT image) confirmed interstitial pneumonitis or pulmonary fibrosis 6)Severe emphysema, chronic bronchitis, asthma 7)History of drug-induced pneumonia or severe drug allergies 8)Uncontrolled diabetes despite continuing treatment of insulin 9)Unstable angina, cardiac infarction within 6 months before enrollment 10)A fever of over 38 degrees 11)Continuous systemic administration of steroid or immunosuppressant 12)Pregnant women 13)Patients with severe mental illness 14)Unsuitable patients judged by the attending physician
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The ratio of the patients who completed chemoradiotherapy using IMRT | — |
Secondary
| Measure | Time frame |
|---|---|
| safety, progression free survival, overall survival, first relapse site | — |
Countries
Japan
Contacts
Public ContactHideyuki Harada
Shizuoka Cancer Center Radiation Oncology
Outcome results
None listed