Selective bladder preservation with curative intent consisting of induction chemoradiotherapy plus partial cystectomy for muscle-invasive bladder cancer: Phase II multicenter study

Selective bladder preservation with curative intent consisting of induction chemoradiotherapy plus partial cystectomy for muscle-invasive bladder cancer: Phase II multicenter study - Bladder preservation consisting of chemoradiotherapy plus partial cystectomy for muscle-invasive bladder cancer: Phase II multicenter study

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000017739

Enrollment

Registered

2015-06-01

Start date

2015-01-18

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Muscle-invasive bladder cancer

Interventions

Low-dose chemoratiation therapy Partial cystectomy

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Muscle-invasive bladder cancer (cT2-3N0M0) Solitary MIBC, circumscribed within 25% or less of the bladder No involvement of the bladder neck Response to induction chemoradiation therapy

Exclusion criteria

Exclusion criteria: CIS Unfit for low-dose chemoradiation therapy or radical surgery under general anesthesia due to complications

Design outcomes

Primary

Measure	Time frame
Muscle-invasive bladder cancer-free survival in patients with bladder preservation	—

Countries

Japan

Contacts

Public ContactYasuhisa Fujii

Tokyo Medical and Dental University Urology

y-fujii.uro@tmd.ac.jp0358035295

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026