Safety and Efficacy of Excision of Horizontal Canaliculus in Severe Aqueous Deficient Dry Eye

Safety and Efficacy of Excision of Horizontal Canaliculus in Severe Aqueous Deficient Dry Eye - Safety and Efficacy of Excision of Horizontal Canaliculus

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000017723

Enrollment

Registered

2015-07-01

Start date

2015-06-01

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

aqueous deficient type of dry eye

Interventions

once horizontal canalicular excision

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. both of in- and out-patients 2. over 20 years old at the entry 3. dry eye patients diagnosed using the 2006-version criteria of dry eye 4. primary and secondary dry eyes 5. patients who had the history failed punctal occlusion using either punctal plug or surgical procedure

Exclusion criteria

Exclusion criteria: 1. patients having active ocular disease other than dry eyes 2. patients having the problem of general condition 3. patients who are decided to inappropriate as subjects

Design outcomes

Primary

Measure	Time frame
intra- and post-operative complications of horizontal canalicular excision occlusion rate of horizontal canalicular excision change in tear meniscus height improvement of ocular surface epithelial damage	—

Countries

Japan

Contacts

Public ContactSeika Den

The Jikei University School of Medicine, Katsushika Medical Center Department of Ophthalmology

denseika@jikei.ac.jp03-3603-2111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Sep 19, 2026