The efficacy and safety of peripheral nerve block: a randomized controlled study

The efficacy and safety of peripheral nerve block: a randomized controlled study - The efficacy and safety of peripheral nerve block: a randomized controlled study

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000017691

Enrollment

Registered

2015-05-27

Start date

2015-05-28

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Case to undergo mastectomy for malignant breast tumor with/without axillary lymphadenectomy

Interventions

Bolus: 0.375% levobupivacaine 20mL Continuous: 0.25% levobupivacaine 4mL/hr bolus 0.75% levobupivacaine 10mL Continuous: 0.25% levobupivacaine 4mL/hr Bolus: 0.25% levobupivacaine 20mL Continuous: 0

Eligibility

Sex/Gender

Female

Inclusion criteria

Inclusion criteria: Patients (American Society of Anesthesiologists physical status I-III) scheduled for elective mastectomy with/without axillary lymphadenectomy for malignant breast tumor

Exclusion criteria

Exclusion criteria: Patients were excluded if they were younger than 18 years or older than 80 years of age, had a history of allergy to local anesthetics, had a history of neurological disorder affecting the corresponding limb, using opioid or analgesic regularly for chronic pain, or were pregnant.

Design outcomes

Primary

Measure	Time frame
Arterial local anesthetic concentrations	—

Secondary

Measure	Time frame
Pain score Elapsed time until first additional analgesia after surgery	—

Countries

Japan

Contacts

Public ContactTakeshi Murouchi

Sapporo Medical University School of Medicine Department of Anesthesiology

murouchi@sapmed.ac.jp011-611-2111(ext.3568)

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026