COPD
Conditions
Interventions
Acupuncture Once weekly for 12 weeks
Sponsors
National Hospital Organization Toneyama National Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1)COPD determined according to diagnostic criteria and classified as stage II or more using the GOLD criteria. Those rated as grade >= 1 according to modified Medical Research Council dyspnea scale (mMRC). 2)Aged > 40 years 3)Stable patients able to tolerate cardiopulmonary exercise testing to ensure adequate evaluation. 4)Signed agreement to participate in the study
Exclusion criteria
Exclusion criteria: 1)Malignant tumors 2)Active infectious disease 3)Severe heart disease 4)Hepatic failure 5)Renal failure 6)Drug regimen changed during clinical trials 7)Participation in pulmonary rehabilitation programs 8)Judged inadequate to participate in the study by their physicians
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Peak oxygen uptake Endurance time SGRQ score | — |
Secondary
| Measure | Time frame |
|---|---|
| Borg scale O2-pulse VD/VT VE/Vo2 VE/Vco2 Respiratory muscle strength Plasma concentration of norepinephrine Body weight CAT score mMRC dyspnea scale Pulmonary function test (Mostgraph, Expiratory FeNo) 24-h heart rate variability Daily physical activities measured using Activision marker Skeletal muscle mass, bone mass, and fat measured using Dual-Energy X-ray Absorptiometry (DEXA) | — |
Countries
Japan
Contacts
Public ContactKeisuke Miki
National Hospital Organization Toneyama National Hospital Laboratory Chief, Laboratory of Respiratory Science, Division of Clinical Research
Outcome results
None listed