Prospective cohort research for aortic root dilatation and non-elasticity after surgical repair in adults with Tetralogy of Fallot

Prospective cohort research for aortic root dilatation and non-elasticity after surgical repair in adults with Tetralogy of Fallot - TRANSIT

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

JPRN

Registry ID

JPRN-UMIN000017555

Enrollment

100

Registered

2015-05-14

Start date

2015-03-01

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tetralogy of Fallot

Interventions

None listed

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1) Patients with Tetralogy of Fallot after surgical repair under 10 years old 2) Patients aged 20 year or older at registaration

Exclusion criteria

Exclusion criteria: 1) Double outlet right ventricle 2) Complicated heart diseases related to aortic dilatation: bicuspid aortic valve, coarctation of aorta, interruption of aorta 3) Complicated connective tissue diseases related to aortic dilatation: Marfan syndrome, Loeys-Dietz syndrome, and others 4) ineligibles for subjects judged by a doctor in attendance

Design outcomes

Primary

Measure	Time frame
The pace of aortic root dilatation	—

Secondary

Measure	Time frame
1) Incidence of aortic root dilatation 2) Aortic elasticity evaluated by pulse wave velocity 3) Effect of oral medication, especially angiotensin receptor blocker and angiotensin converting enzyme inhibitor	—

Countries

Japan

Contacts

Public ContactHiroki Nagamine

Tokyo Metropolitan Children's Medical Center Division of Cardiology

hiroki_nagamine@tmhp.jp042-300-5111

Outcome results