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Comparative study between non-blinded, randomized, parallel group regarding the preventive effect of the coarse-hydrochloride landiolol for atrial fibrillation after major thoracic vascular surgery

Comparative study between non-blinded, randomized, parallel group regarding the preventive effect of the coarse-hydrochloride landiolol for atrial fibrillation after major thoracic vascular surgery - Comparative study between non-blinded, randomized, parallel group regarding the preventive effect of the coarse-hydrochloride landiolol for atrial fibrillation after major thoracic vascular surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000017551
Enrollment
80
Registered
2015-05-13
Start date
2012-11-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

thoracic aortic aneurysm, thoracic aortic dissection

Interventions

Group treated with the hydrochloride salt landiolol Group treated without the hydrochloride salt landiolol

Sponsors

Hiroshima University Institute of Biomedical and Health Sciences Applied Life Sciences Surgery
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: (a) Age at the time of obtaining informed consent of patients aged 20 years or older (b) Patients scheduled for thoracic aortic aneurysm or dissection underwent replacement surgery. (c)Patient consent is obtained in writing with respect to participation in the study

Exclusion criteria

Exclusion criteria: Corresponding to patient contraindications hydrochloride landiolol Patients with acute myocardial infarction within 3 days. Patients with supraventricular arrhythmia that might need treatment. Patients with severe heart failure (NYHA III degrees or more just before surgery, EF less than 35%). Patients with atrial fibrillation cause of electrolyte abnormalities, WPW syndrome and hyperthyroidism. Diastolic blood pressure / systolic patients less than 90/60 mmHg. Patients with severe asthma. Patients who take an oral antiarrhythmic drugs or beta blocker. Patients who were found to be inappropriate physician to carry out the study.

Design outcomes

Primary

MeasureTime frame
The proportion of patients with atrial fibrillation coarse-until 7 days after surgery occurred.

Countries

Japan

Contacts

Public ContactKeisuke Watadani

Hiroshima University Institute of Biomedical and Health Sciences Applied Life Sciences Surgery

kwatadani@hiroshima-u.ac.jp0822575218

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026