Randomized clinical trial of preventive effect of acetazormide acetate for marked intraocular pressure (IOP) elevation after cataract surgery in eyes with open-angle glaucoma.

Randomized clinical trial of preventive effect of acetazormide acetate for marked intraocular pressure (IOP) elevation after cataract surgery in eyes with open-angle glaucoma. - Prevention of IOP elevation after cataract surgery in eyes with open-angle glaucoma

Status

Active, not recruiting

Phases

Unknown

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000017526

Enrollment

Registered

2015-05-13

Start date

2014-09-09

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Open-angle glaucoma

Interventions

1) Administering 2 tablets of acetadormide acetate for the first operated eye at 1 hour preoperatively, 30 eyes, 30 patients. 2) Administering 2 tablets of acetadormide acetate for the first operated

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: Patients with open-angle glaucoma of 40 years or older

Exclusion criteria

Exclusion criteria: 1)macular or corneal pathology 2)history of ocular surgery and inflammation 3)pupil diameter of less than 5.0mm when dilated 4)any difficulty in follow-up or examination

Design outcomes

Primary

Measure	Time frame
1.IOP measured using a rebound tonometer (I care) in a supine position. 1) Preoperatively 2) At the conclusion of surgery..IOP is adjusted to a range between 15 and 25 mmHg. 3) 60 minutes postoperatively 4) 180 minutes postoperatively 5) 300 minutes postoperatively 6) 420 minutes postoperatively 7) 24 hours postoperatively	—

Secondary

Measure	Time frame
2. Postoperative inflammation Flare intensity at 5 hours postoperatively 3. Wound status Anterior segment-optical coherence tomography at 5 hours postoperatively 4. Others Visual acuity, refraction, corneal astigmatism	—

Countries

Japan

Contacts

Public ContactKen Hayashi

Hayashi Eye Hospital Department of Ophthalmology

hayashi-ken@hayashi.or.jp092-431-1680

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026