Phase I and II trial of lens block during electron radiation therapy for low grade lymphoma arising from conjunctiva

Phase I and II trial of lens block during electron radiation therapy for low grade lymphoma arising from conjunctiva - Phase I and II trial of lens block

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

JPRN

Registry ID

JPRN-UMIN000017517

Enrollment

Registered

2015-05-12

Start date

2015-05-12

Completion date

Unknown

Last updated

2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Low grade malignant lymphoma arising from conjunctiva

Interventions

Before use of the block, ipsilateral cornea and conjunctiva receive local anesthesia. After the locations of the block, the conjunctiva is irradiated 2Gy with electron beam in one session. Patients

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1. 20 years old or older 2. Localized low-grade lymphoma arising from conjunctiva 3. It is supposed that the use of lens-bock is effective. 4. Consent from the patient for participating in the study is obtained.

Exclusion criteria

Exclusion criteria: 1. Retro-bulbar lesion 2. Allergy for local anesthesia 3. History of lens exchange 4. Infectious diseases or other disorders of the eye 5. Patients who are determined inadequate for the use the lens block from the viewpoint of the main investigator

Design outcomes

Primary

Measure	Time frame
Adverse effects of lens block	—

Secondary

Measure	Time frame
1 Radiation effects for the lymphomas a local control rate b overall survival c progression free survival 2 Frequency of cataracts after the treatment	—

Countries

Japan

Contacts

Public Contactkeisuke Sasai

Juntendo University Department of Radiation Onclogy

ksasai@juntendo.ac.jp3-3813-3111

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026