Major depressive patitents from 50 to 79 years old and healthy controls
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1) Age range, 50 - 79 years old. 2) Major depression detected by DSM-IV. 3) HAM-D, below 10 points. 4) Out or In-patents in Gunma university hospital. 5) All the subjects provided their written informed consent.
Exclusion criteria
Exclusion criteria: 1) The subjects can not receive MRIbecause of medical condition, e.g., heart pacer. 2) The subjects have the following illness, i.e., DM, stroke, AMI, angina pectoris, liver dysfunction, renal dysfunction, cancer, epilepsy, or dementia. 3) The subjects have been receiveing the following drug treatments, i.e., hypercholesterolemia, hypertension, steroid, or insomnia. 4) Involuntary admission 5) Hospitalization for Medical Care and Protection 6) unconscousness 7) The patient without notice of diagnosis. 8) The subjects disallowed by medical staff in this research
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| CANTAB, HOMA-R, voxel based morphometory, GABA-A recepror distribution | — |
Secondary
| Measure | Time frame |
|---|---|
| Neuronal connectivety | — |
Countries
Japan
Contacts
Gunma university hospital Department of Psychiatry and Neuroscience