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The association among cognitive function, arteriosclerosis and GABA-A receptor in geriatric depressive patients.

The association among cognitive function, arteriosclerosis and GABA-A receptor in geriatric depressive patients. - Geriatric depression

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
JPRN
Registry ID
JPRN-UMIN000017484
Enrollment
80
Registered
2015-05-20
Start date
2015-05-20
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Major depressive patitents from 50 to 79 years old and healthy controls

Interventions

Iomazenil spect

Sponsors

Department of Psychiatry and Neuroscience, Gunma university hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1) Age range, 50 - 79 years old. 2) Major depression detected by DSM-IV. 3) HAM-D, below 10 points. 4) Out or In-patents in Gunma university hospital. 5) All the subjects provided their written informed consent.

Exclusion criteria

Exclusion criteria: 1) The subjects can not receive MRIbecause of medical condition, e.g., heart pacer. 2) The subjects have the following illness, i.e., DM, stroke, AMI, angina pectoris, liver dysfunction, renal dysfunction, cancer, epilepsy, or dementia. 3) The subjects have been receiveing the following drug treatments, i.e., hypercholesterolemia, hypertension, steroid, or insomnia. 4) Involuntary admission 5) Hospitalization for Medical Care and Protection 6) unconscousness 7) The patient without notice of diagnosis. 8) The subjects disallowed by medical staff in this research

Design outcomes

Primary

MeasureTime frame
CANTAB, HOMA-R, voxel based morphometory, GABA-A recepror distribution

Secondary

MeasureTime frame
Neuronal connectivety

Countries

Japan

Contacts

Public ContactNarita Kosuke

Gunma university hospital Department of Psychiatry and Neuroscience

knarita@gunma-u.ac.jp027-220-8186

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026