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A Multi-Site Study on the Brain Function and Structure of Patients with Eating Disorders

A Multi-Site Study on the Brain Function and Structure of Patients with Eating Disorders - A Multi-site Study on the Brain of Eating Disorder Patients

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
JPRN
Registry ID
JPRN-UMIN000017456
Enrollment
250
Registered
2015-07-01
Start date
2015-07-01
Completion date
Unknown
Last updated
2026-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anorexia nervosa Bulimia nervosa

Interventions

None listed

Sponsors

Japan Eating Disorder Consortium (JEDC)
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: Patients with anorexia nervosa(AN) and bulimia nervosa (BN) who fulfill the criteria of Diagnostic Statistical Manual for Mental Disorders version 5. AN patients include both restrictive type and binge-purge type. Persons recovered from AN and BN. Healthy Persons.

Exclusion criteria

Exclusion criteria: We exclude persons who are implanted a pacemaker or an intracranial clip, and persons with an accidental metallic implant object and its possibility, or an orthodontic bridge. Patients with a past history of clausrtophobia, head trauma, or neurological disorders are excluded. Although persons with a past history of psychiatric diseases would be excluded, AN or BN patients who suffer from depression, anxiety disorder, or personality disorder would not be excluded because these diseases are frequently comorbid with AN and BN. Pregnant women, breast-feeding women would be excluded. Women who turned out to be pregnant after registration would also be excluded.

Design outcomes

Primary

MeasureTime frame
Data of Voxel Based Morphometry, Diffusion Tensor Imaging, and resting state functional MRI after treatment

Secondary

MeasureTime frame
Clinical Global Impression Severity Scale (CGI-S), Global Clinical Score (GCS), Eating Disorder Inventory version 2 (EDI II), Eating Disorder Examination Questionnaire (EDE-Q), Beck Depression Inventory version 2 (BDI-II), State Trait Anxiety Inventory (STAI), Self Efficacy Scale (SES), Maudsley Obsessional-Compulsive Inventory (MOCI), Barratt Impulsiveness Scale (BIS-11), Toronto Alexithymia Scale (TAS-20), Autism Spectrum Quotient (AQ).

Countries

Japan

Contacts

Public ContactYsasuhiro Sato

Tohoku University Hospital Department of Psychosomatic Medicine

yassat@hosp.tohoku.ac.jp022-717-7327

Outcome results

None listed

Source: JPRN (via WHO ICTRP) · Data processed: Jul 3, 2026